Episode 34

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Published on:

6th Nov 2025

Turning Trauma into Purpose: Sam Peterson's Journey from Battlefield to Healing - #34 - Oct 18, 2025

Transforming Mental Health: The Power of Neurostimulation and Innovative Therapies with Sam Peterson

In this episode of the Neurostimulation podcast, host Dr. Michael Passmore interviews Sam Peterson, a former army bomb technician and co-founder of Patriot Power Up, who now leads Mind Spa Denver. Sam shares his personal journey from battling PTSD and traumatic brain injury (TBI) to pioneering innovative mental health therapies. He explains the neurobiology of trauma, the impact of neuroinflammation, and the effectiveness of treatments like Ketamine, transcranial magnetic stimulation (TMS), and hyperbaric oxygen therapy in providing rapid relief and promoting neuroplasticity. The discussion highlights the importance of innovative, individualized approaches to mental health care for veterans, first responders, and trauma survivors, aiming to revolutionize treatment protocols and improve lives.

https://www.mindspadenver.com/

00:00 Introduction to Sam Peterson and His Mission

01:48 Sam's Journey from Battlefield to Mental Health Advocate

03:03 Understanding the Neurobiology of Trauma

04:39 The Role of Inflammation in Mental Health

12:36 Innovative Treatments at Mind Spa Denver

22:55 Success Stories and Future Vision

27:17 Challenges and Opportunities in Mental Health Care

36:13 Conclusion and Final Thoughts

Transcript
Mike:

Welcome back to the Neurostimulation podcast.

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Today I'm speaking to Sam Peterson,

a former army bomb technician and

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combat veteran who survived the

battlefield only to face a different

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kind of war, the battle with

PTSD and traumatic brain injury.

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But out of that darkness came purpose.

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Sam is the co-founder of Patriot

Power Up, an inpatient program that

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delivers rapid relief for PTSD and TBI.

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And he also runs Mind Spa Denver, an

outpatient clinic that's pioneering

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cutting edge therapies from TMS

and Ketamine to interventions

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that are based on neuroplasticity.

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His work really is transforming the

mental health care landscape for veterans

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first responders and trauma survivors.

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So today I'm really excited to talk to

Sam about the neurobiology of trauma.

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Inflammation in particular might be

the real villain in mental illness

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in general, and what it takes to

turn pain into purpose through

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mission-driven entrepreneurship.

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Sam, welcome to the show.

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Thanks for being here.

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Sam: Oh, thanks for thanks

for having me, Michael.

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It's been I'm glad we

finally got to do this.

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We've been doing a little bit back and

forth on scheduling, but I'm really happy

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to be here 'cause this message is really

important for everyone's audience to hear.

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Mike: Definitely.

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Yeah.

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And thank you for your patience in

terms of the rescheduling and that.

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But yeah, I'm glad that we've

been able to get together today.

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So I'm curious as a way of

introducing yourself maybe, it's

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just such a fascinating journey.

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So from your experience in disarming

bombs all the way now to rewiring brains,

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can you walk us through your personal

journey and how those experiences

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led you to found Patriot Power Up?

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Sam: Yeah.

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So I, I've actually, I've shifted over

to take on the CEO role at Mind Spa Now.

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I still have a peripheral

relationship with Patriot Power Up.

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But how I got here was just out of pain.

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One of the things that they don't tell

you when you sign up for the military.

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Regardless of which job you sign up

for is how high the suicide rate is.

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And it turns out that being a bomb

technician has an incredibly high suicide

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rate, especially during a time of war.

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And that's mostly because of the

constant exposure to traumatic blast

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that we're continuously getting hit with.

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And I suffered quite a bit, but really my.

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Contemporaries, all of my peers had

it way worse than I did, and I saw

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firsthand just how that exposure to

traumatic blast leads to suicide.

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Mike: Yeah.

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Help us to understand that.

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On the one hand, obviously it

makes sense in terms of the stress

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associated with those experiences,

but I'm also curious about how.

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Just the physical exposure to that

sort of energy on a repetitive basis

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increases the risk for depression,

despair, suicidal thoughts.

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Sam: Yeah.

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To understand the nature of how TBI

causes those downstream consequences,

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we need to understand the cellular

biology of a traumatic brain injury.

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And one of the main things that happens.

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So first you have your

initial injury to the axon.

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So imagine your brain, your

neurons rather, are made of Legos.

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So we have this neuron

that's made of Legos.

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It receives an injury of some

sort, whether it's a blast or

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blunt force, and it breaks Legos

scatter all over the floor.

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Those Legos are tau proteins.

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Our neurons are actually

made of these tau proteins.

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Normally, the immune system of

the brain, your glial cells.

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Sit in a sentinel like role.

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They actually shepherd with.

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There's new studies that show

that they shepherd quite a bit

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of neuronal function as well.

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So the shepherd cells are sitting there

doing their job, maintaining the area

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around your neuron, and when they see

all these legos all over the floor.

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They go, oh crap, I need to clean this up.

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This looks like a foreign contaminant.

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There is cellular detritus in my area.

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I gotta pick these legos up off the floor.

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So the first thing that your glial

cells do is they enter a state called

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M1 activation or microglial priming.

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They, put on their little soldier hat.

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They grab their gun and they start

shooting reactive oxygen species

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at these Legos to neutralize them.

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So just like they would do

if it was a harmful bacteria.

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So they shoot these reactive

oxygen species and then

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they move to a third phase.

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It's called a pha acidic role.

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So their job is to go in and

clean all these legos up and

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absorb them and digest them.

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That third step takes a lot of energy.

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If they, if your glial cells don't

have enough energy to complete step

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three, they get stuck in step two.

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So that microglial priming step where

they're just firing off at all of

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this foreign contaminant, if you will.

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That causes a ton of inflammation.

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It creates a neurotoxic environment,

and that eventually starts to

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break down and kill your neurons.

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It causes a number of issues including

what's called tau hyper phosphorylation.

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So you shoot the Legos with

the reactive oxygen species.

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Think hydrogen peroxide.

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The Lego gets coated in that hydrogen

peroxide and it just, it's floating

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around in the space between your

cells and it starts sticking to other

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cells, and that goes on long enough

and you get these big balls of these

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hyper phospho related tau particles.

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They're called neurofibrillary tangles.

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And when those tangles get big

enough, they start to invade

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the neurons around them.

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This mess spreads throughout the rest

of the room and throughout the house.

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That is your brain.

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Over time, those balls, those

neurofibrillary tangles get bigger and

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bigger until they affect the neurons

around them and start killing them.

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And this process goes on and on.

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It doesn't stop until it kills you.

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You'll see if you one look at the

literature too, just anecdotally,

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look at someone who has significant

either blast or blunt force trauma

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injuries, and you'll see, imagine

someone's functionality starts up here.

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They have a traumatic brain injury.

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Boom.

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Immediately their functionality falls, and

then after a while they start to recover.

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They recover a little bit, and then

we just see a plateau, and then that

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plateau goes on until about 10, 15, 20

years later, boom, falls off a cliff

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and they just fall into dementia,

and that's why, and that's a process.

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I don't hear anybody talking about

and that's one of the targets

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of our therapeutic modalities is

getting to the heart of that issue.

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We gotta clean up those Legos.

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We gotta get that crap out

of the intercellular space

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so it doesn't kill you.

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Mike: Yeah.

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Yeah, no, that's, I really appreciate

the way that you use those metaphors

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to illustrate that process.

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I've never heard it explained

that way, but it makes so much

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sense and it's fascinating and

worrisome as well, because.

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Exactly the same sort of pathophysiology

in the nervous system is part of what

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causes Alzheimer's disease, right?

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So as you say, addressing that

and correcting that as early as

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possible is gonna be important

for all kinds of reasons.

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Not only in terms of current functioning

and health, but also to reduce the future

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risk of neurodegenerative disorders.

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Sam: Oh yeah.

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Even Alzheimer's dementia, chronic

traumatic encephalopathy and

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Parkinson's are all tauopathies.

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They all fall into this same family,

and if we can address this root cause,

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and really what we're talking about is a

hypoxic issue, the problem is that your

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glial cells can't make enough energy.

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They can't make enough

energy to clean up the mess.

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The rate limiting factor here is oxygen.

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If you don't have enough oxygen,

you can't complete the Krebs cycle.

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And for everybody's watching,

who doesn't know what that is?

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That is cellular respiration.

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That is the process our cells use

to convert glucose, oxygen, and a

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couple other chemicals into A TP.

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A TP is what our cells run on.

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If you are not giving your cells

enough cellular gasoline, they

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cannot complete these tasks.

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And if this goes along

enough, you, it'll kill you.

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Mike: Yeah.

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Yeah.

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So do you think it's as far as the

linkage, the linkage between people

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becoming frustrated and then developing

depression and then despair, and

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then suicidal thinking, is it's,

I imagine, and perhaps it's partly

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related to the physiological impact

as you're describing, but also partly

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related psychologically to feeling.

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If someone's having trouble with

concentrating and they're having

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trouble with functioning, whether it's

in their job or their relationships,

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then they start to get discouraged and

frustrated and they try medications

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maybe, and that's not working.

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And is that kind of how

the cascade usually goes?

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Sam: So yes.

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And we still have this biological

process, this knock on biological

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process that's going on.

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If you're looking at the brain and

you're just looking at the brain from

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like a blood vessel perspective, you'll

see that, our arteries come up they

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damn near innervate the amygdala, our

fight, flight, or freeze function,

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our hind brain, our animalistic brain.

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But when you look at the prefrontal

cortex, when you look at these

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outer regions of the brain,

specifically the ones that are

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responsible for our higher cognitive

functions, you'll see that they're.

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Or sorry that the blood

vessels are very small.

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It doesn't take a whole lot of

inflammation before all of a sudden,

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red blood cells can't deliver oxygen.

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So you have a big problem there.

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Okay.

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Now, we can't do cellular respiration

because we don't have oxygen.

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Your cells don't just die or a

traumatic brain injury would be

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almost instantaneously fatal.

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What happens is if your cell, if your

red blood cells can't get through

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these vessels, they go, okay, cool.

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Check Raj.

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We're gonna switch over to plan B and

they switch over to a process of energy

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creation called anaerobic glycolysis.

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It's a fermentation process revolving

around sugars in the brain and

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'cause all your brain has is this

glucose, it can't get the oxygen.

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So switching over to anaerobic glycolysis.

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It creates a lot of waste products,

this fermentation process.

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So imagine if we're doing

cellular respiration over here.

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This is like burning natural gas.

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Is there some offgassing?

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Yes.

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But it's nothing that your cellular

structure can't start to clean up.

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That it's pretty limited as

far as like creating nastiness.

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Versus anaerobic glycolysis.

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Now we're burning a wood stove.

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I'm not sure if you've ever been to,

any of the towns here in Colorado,

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but just imagine a valley full of

houses like in Aspen, Colorado.

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If all of those houses started

burning their wood fire stove,

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how long would it be before you

couldn't breathe in the valley?

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Perfect example of what's happening

in your cells and that toxicity.

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Breeds more inflammation.

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So you can see very quickly that this

process just, it knocks on itself.

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And when we're talking about depression or

anxiety or PTSD very broad strokes here.

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This is a bit of an over simplifi

simplification, but if you were to

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look at the brain, if you were to open

up, someone's skull, and you could see

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the electrical firing of the brain.

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Of someone who had

depression, anxiety, or PTSD.

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What you would very broadly see is

an underactive prefrontal cortex

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and an overactive hind brain.

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And that's why.

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Mike: Yeah, no, that makes sense.

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And I think that it's really interesting

that the neuroinflammation piece seems

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to be totally understandable, unifying

principle that's at the root of a lot of

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this, and I think that goes along with a

lot of the recent research that is showing

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that, as a result of other factors, like

cortisol, hyper, excessive amount of

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cortisol related to stress and how that

promotes the neuroinflammation as well.

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Yeah, no, thanks again

for explaining all that.

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So I'm curious, so at Mind Spa Denver, can

you describe some of your philosophy in

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broad strokes when it comes to treating

patients, combining these modalities,

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like the repetitive transcranial magnetic

stimulation and things like ketamine

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therapy, in order to not only address the.

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Like what we're talking about, things

like the neuroinflammation, but also

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look at promoting neuroplasticity.

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Sam: Yeah, absolutely.

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So our thesis at MInd Spa is that in

order to solve these problems to get

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to the root cause, we have to address

that inflammatory cascade first.

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Otherwise, we are pushing

a boulder up a hill.

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Just like you see someone who's

struggling with chronic depression,

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that's treatment resistant.

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Same with post-traumatic

stress disorder anxiety.

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We have to fight that inflammation battle

before we can ask the brain to rewire.

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Because if I'm asking the brain to

create new connections, one, it again

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costs a lot of energy to do that, which

the brain in those areas doesn't have.

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And two, we're dealing with, we're

dealing with an area that's just.

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Cramped in by these

inflammatory cytokines.

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There's a non permissive environment.

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Imagine trying to, it's like trying

to grow a plant after you've just

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sprayed Roundup all over your garden.

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Not gonna work.

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Got poison everywhere.

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So our first sorry.

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Our first treatment methodology is,

let's clear out that inflammation.

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That's one of the big reasons

that we use ketamine infusion

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therapy as a frontline treatment.

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So Ketamine, is a, drug that's used every

day in pediatric medicine, bariatric

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medicine, as well as mental health.

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It is what's called an

NMDA receptor antagonist.

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Basically, it goes into

your cells and it goes, Hey.

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There's no glutamate in here.

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Now, taking a step back, glutamate is

the primary excitatory neurotransmitter.

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It's the neurotransmitter that's

telling our cells to make energy

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to do all of these functions.

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So ketamine goes up to the receptor

on the outside of the cell, knocks

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on the door and says, Hey, there's

no glutamate out here, guys.

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We need some more.

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Bring it out.

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Everybody out.

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Let's go.

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So your cell expels a large

amount of its glutamate into the.

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The space outside your cell is the

intracellular space, and that's why

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we see a retraction in consciousness.

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That's what the K hole really is.

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Is your cells going?

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Yeah.

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Guys like take a lunch break.

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The cool thing is.

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After that, glutamate takes a lunch

break, 15 to 45 minutes later,

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depending on method of administration.

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When it comes back into the

cell, it doesn't go back

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to doing the same function.

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One molecule.

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If it was like, let's just say it was

stimulating a mitochondria to make

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energy, that same molecule doesn't

go back to doing that same task.

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It gets reallocated by

the cell and that is why.

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Ketamine is like this control

alt, delete for the brain.

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That's why it's effective in

treating acute suicidality.

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It also triggers a

downregulation in inflammation.

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Really it halts your brain from

creating certain inflammatory cytokines.

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So pro-inflammatory markers.

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It just puts a halt on that.

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So ketamine is a great way for us

to just flip some switches in the

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brain and give someone immediate

relief from those symptoms.

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And when I say immediate, I'm talking

one to two one to two infusions.

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So anywhere from, one to four

days, and someone can start

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to feel immediately better.

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It's a very powerful tool, especially

when it's done responsibly.

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Then, then we and then we have

a couple other treatments, but

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I've been talking three minutes.

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Mike: No.

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That's great.

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I think that's awesome.

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I think I really, I think it's really

important to underscore this issue

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about fast acting relief, right?

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Because I think that.

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And I've been in psychiatry for 20 years

and I think it's just so frustrating for

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patients how long they have to wait to

get better on legacy treatments, right?

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So something like ketamine that can offer

that rapid relief is really critical

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and it's really emphasizing that.

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So that's really interesting.

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And it makes a lot of sense and

I think, yeah, it's given what we

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were just talking about the severity

of symptoms and the complex neuro.

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The complex pathophysiology of the

whole thing, particularly in terms

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of the neuroinflammation piece.

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It makes total sense to have to, in

a sense, do that intervention right

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up front to reset the brain in that

sense that you're talking about.

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And from there, I'm curious,

so how then might that go?

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I know it's not, it's not really possible

to give details 'cause the other advantage

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of this kind of an approach I would

imagine is that it's, it lends itself to.

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Highly personalized kinds of

treatment protocols, right?

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So that there'd be that careful assessment

phase and then, offering various

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different treatment modalities that are

tailored to someone's individual needs.

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But in general terms, if someone's coming

with say, like a significant emotional.

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Post-traumatic or TBI related issues,

then the ketamine to start, and then would

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that potentially just lead into a course

of r tms or what might be the next steps?

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Sam: Yeah, so again, it

really depends on it.

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It depends on the patient of course,

and what they're coming in for.

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But.

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Broad strokes, ketamine, also, what I

forgot to mention is ketamine increases

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neuroplasticity by upregulating

brain derive neurotropic factor.

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Very important piece when we're

talking about rewiring the brain.

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The next thing that we typically move

on to, and this is again, broad strokes.

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This is if someone's doing our whole

protocol, we do offer these a la carte.

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But we, if in a perfect world.

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Someone starts on ketamine

after that first week.

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Then we have an approval for

transcranial magnetic stimulation,

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and we also start them on hyperbaric

oxygen therapy simultaneously.

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Yeah I'm sure this is the

Neurostimulation podcast.

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I'm sure you guys talk

about TMS all the time.

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But just, just

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Mike: for sure.

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Sam: Yeah.

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Just for anybody that's not walking, I'll

throw throughout the quick, explainer.

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It for layman's, for the

layman's terms basically, TMS.

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For anybody who's never heard

of it is MRI technology.

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We take an MRI coil that MRI coil

creates a magnetic field that we

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place that MRI coil on the surface

of the scalp in a specific spot for

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treating major depressive disorder.

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It's the dorsal later left

dorsal later prefrontal cortex.

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That magnet creates that magnetic

field under the surface of the

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scalp and that magnetic field.

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Again, very high level.

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Trick your neurons into clustering

more densely in a network.

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So you know how we do TMS, we

also take it to the next level.

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Our TMS techs really work to help

our patients stimulate that area,

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or rather activate that area

while they're stimulating it.

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So we do, a lot of DBT workbooks

sometimes playing puzzles or playing

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like brain games with our patients

while their brain is getting

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stimulated and that has shown to be.

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Much more efficacious,

long-term for our patients.

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And then, through this whole process,

like we are trying to rewire the

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brain, we're trying to get your

brain cells to do different things.

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Anytime you're asking a cell to branch

out and create new connections, you're

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asking it to spend a lot of energy.

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So we talked about, the TBI.

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And that neuroinflammatory process,

that's where the HBO comes in.

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That's where hyperbaric oxygen therapy can

turn this entire thing up to a hundred.

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Because we have a rate limiting

factor in our physiology that keeps

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our brain from getting more oxygen.

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It's our lungs.

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We can only breathe so much unless

you're doing, holotropic breath

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work every single day, you, there's.

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There's no way to get your cells the

energy they need to do all this work

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in the most effective way possible.

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So that's where the hyperbaric

oxygen therapy comes in.

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And for anybody that's not

familiar with hyperbaric.

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It's a wonderful treatment that,

here in the states is FDA approved

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for 15 different conditions.

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A lot of them are around wound

healing, like diabetic wound ulcers,

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non-healing wounds radiation poisoning.

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It's also dA approved

for treating the Bens.

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There's a whole list.

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Currently traumatic brain injury and

PTSD are not part of that list, but

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there's a ton of peer reviewed research

and meta-analyses that show that this

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is effective in treating these disorders

for the reasons I'm about to explain.

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Big picture here.

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So you get inside a chamber.

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The chamber is closed off and we

increase the pressure inside the

379

:

chamber by pumping air in there.

380

:

We can.

381

:

We typically treat, depending on

the disorder, anywhere from 1.3

382

:

atmospheres to two atmospheres.

383

:

That's the sweet spot for TBI 1.5

384

:

is where the most the most

research has been done.

385

:

To give you an example that,

that'll make a little more sense.

386

:

If you're diving you're getting about two

atmospheres, absolute of pressure when

387

:

you're at about 33 feet under the water.

388

:

So you're down at this pressure,

you're in this chamber, and then you're

389

:

breathing in concentrated oxygen.

390

:

That forces oxygen into your blood plasma.

391

:

So now, talked earlier about those

red blood cells and how we're running

392

:

into these inflamma inflammatory

issues that are keeping our red

393

:

blood cells from getting to where

they need to deliver oxygen.

394

:

Now we've just taken those

guys out of the picture.

395

:

We don't need 'em anymore.

396

:

We have now created a pipeline directly to

the cells to bathe your brain in oxygen.

397

:

Now all of a sudden your

cells are supercharged.

398

:

They are super excited.

399

:

We have put nitroglycerin in those gas

tanks and they start producing a lot more.

400

:

In fact, doing 20 sessions of hyperbaric

oxygen therapy has been shown to increase

401

:

stem cell production by up to eight fold.

402

:

So brand new cells, whole body.

403

:

We're also downregulating inflammation.

404

:

And when you use these things in concert.

405

:

The results that we've seen

are dramatic and profound.

406

:

To give you an example, at Patriot

Power Up, we were using all of these

407

:

modalities together in an inpatient

program along with culturally

408

:

competent talk therapy for veterans.

409

:

What we saw in that program was

astounding within 14 to 17 days.

410

:

Full symptom remission.

411

:

We're talking, guys are coming in.

412

:

This is an inpatient program,

so they're not coming in 'cause

413

:

they're having a good day.

414

:

So they, these guys started,

at a PHQ nine of 20 plus.

415

:

That's pretty damn high

on the depression scale.

416

:

GAD seven.

417

:

Same in the same zone.

418

:

And as well as a very high PCL

five, which is a measure for

419

:

post-traumatic stress disorder.

420

:

Within 14 to 17 days, they had

achieved symptom remission.

421

:

They no longer qualified

for the diagnosis.

422

:

And if you look at the

thresholds, they were under the

423

:

mild threshold within 21 days.

424

:

Within 21 days, over 90% of the patients

we treated were at zeros across the board.

425

:

Mike: Wow.

426

:

Sam: Yeah.

427

:

And the awesome thing is they got

better and they stayed better.

428

:

We looked at their executive function

before and after, so we used CNS vital

429

:

signs, pretty much the gold standard

for anyone's watching who's a veteran.

430

:

If you've ever taken the army, a NAM

exam, which is a neuropsych battery,

431

:

so we did that again pre and post.

432

:

What we saw was pretty astounding

with our PTSD patients.

433

:

The average increase in executive function

after 45 days of treatment was 40%.

434

:

40% increase in executive function.

435

:

That's pretty damn awesome for our

TBI patients, like this is where

436

:

things get a little astounding.

437

:

125% was the average increase

in executive function.

438

:

And again, symptoms gone.

439

:

The.

440

:

These numbers are one incredible

they're super exciting.

441

:

There's a ton more data that we have to

collect, but like we're knocking on the

442

:

door of getting to the root cause here

and people are starting to take note.

443

:

Mike: Yeah, no, I think that's really

important to emphasize also, and I

444

:

think part of why it's important is

that, as you say, you know this, what

445

:

you're offering now on the outpatient

side is grounded in that experience in.

446

:

In people who were ill and dysfunctional

to the point where they needed to be

447

:

hospitalized, and it's just incredible.

448

:

Just those results are fantastic.

449

:

So congratulations to you and your team.

450

:

I think that's, oh,

451

:

Sam: thanks.

452

:

Mike: Great that you're now able to

expand the offering out into folks

453

:

that are in the community and that are

similarly suffering and looking for help.

454

:

That's fantastic.

455

:

Sam: Yeah, we've been able to

really take this to the next level.

456

:

So we've we've started a program

called our TRICARE Preferred program.

457

:

So if you're not familiar with

tricare, that is the insurance that

458

:

active duty personnel in the us

reserve National Guard and military

459

:

retirees and their families have.

460

:

So if someone qualifies for transcranial

magnetic stimulation through.

461

:

Through Tricare, which is three

failed antidepressant medications

462

:

of sufficient dose and duration,

they qualify for our program.

463

:

So our program is you qualify

for TMS and once you qualify for

464

:

TMS, they'll typically approve

between 30 to 60 TMS treatments.

465

:

And when they do, we give the patient

that many sessions of hyperbaric

466

:

oxygen therapy for free, as well as

six sessions of ketamine for free.

467

:

And since it's outpatient and not

inpatient, we're able to bill for

468

:

the talk therapy so we can put

all of this protocol into a single

469

:

outpatient experience for our patients.

470

:

I'm beyond excited about rolling this out.

471

:

We're starting here in Colorado and we're

very rapidly looking to expand to the rest

472

:

of the nation so that we can just make

veteran suicide go away because that's

473

:

why these people are killing themselves.

474

:

They don't, one, they don't have any hope.

475

:

And two, the brains are inflamed.

476

:

If we can fix that and rewire

the brand, we can end this.

477

:

It's not that hard and honestly,

it's not that expensive either.

478

:

Mike: Yeah.

479

:

Yeah.

480

:

No, I think it's just such a great vision

and yeah I, it's just so encouraging and

481

:

and it's so great to hear the message.

482

:

I'm sure that Veterans Affairs

is interested as well, right?

483

:

In terms of, as you say, just

doing as much as they can to

484

:

yeah maybe not, hard to say.

485

:

What are.

486

:

Sam: Under the new administration

things are gonna change under

487

:

the Biden administration.

488

:

It was like beating your head against

a brick wall that has spikes in it.

489

:

They didn't, the VA is all, at

least the last administration,

490

:

the VA was about the va.

491

:

They were trying to federalize everything.

492

:

They refused to give what's

called a, community care consult.

493

:

And there's a couple reasons for that.

494

:

One of them is the VA and the DOD,

the Department of Defense do not

495

:

like hyperbaric oxygen therapy.

496

:

It's not part of the formulary.

497

:

And I got in a pretty knockdown

drag-out argument with a

498

:

psychiatrist from Vail about this.

499

:

It's it's not in the formulary.

500

:

And I was like, do you know why

you think that this is a bad idea?

501

:

And he is what do you mean?

502

:

And I was like, do you know

why you have this opinion that

503

:

you're spouting right now?

504

:

He is it doesn't work.

505

:

And I was like.

506

:

Okay, let me tell you why you think this.

507

:

There were three studies that

were done by the Department of

508

:

Defense, one by the Army, one by

the Navy, and one by the Air Force.

509

:

These were sham controlled studies.

510

:

A sham control.

511

:

In a sham control study, you have

a treatment group and a group that

512

:

thinks that they're getting it.

513

:

It's like a placebo, for things like

hyperbaric oxygen therapy, it's a

514

:

little difficult to like make someone

think they're going to pressure.

515

:

So what they did with the sham

group is they took them down in

516

:

the chamber at, with room air.

517

:

So no, no concentrated oxygen.

518

:

They brought the individuals

in the study down to 1.3

519

:

atmospheres, absolute.

520

:

They brought them down to a therapeutic

depth, and then they kept them

521

:

there for an hour for 40 treatments.

522

:

In each one of these studies,

they gave them a therapeutic

523

:

dose of the therapy, and then the

treatment group went down to 1.5

524

:

atmospheres, absolute, and

breathed in concentrated oxygen.

525

:

Both groups got better.

526

:

And they called it the placebo effect,

and they only used one method of patient

527

:

reported of patient reported symptomology

to justify calling it the placebo effect.

528

:

And I talked to the PhD who wrote

this, and I was like, can you please

529

:

hand me your doctorate so I can just

pair it up in front of your face?

530

:

Because this is called Henry's

Law of Fucking Chemistry.

531

:

A gas will diffuse into a liquid at a

given rate, and an increase in partial

532

:

pressure will increase the amount

of gas that diffuses of that liquid.

533

:

That's exactly what

happened with these people.

534

:

You put them at a ther, you gave them

a therapeutic dose, you downregulated

535

:

inflammation in their brain, which is

the primary issue that they have with

536

:

PTSD, anxiety, depression, and TBI.

537

:

So you relieved their symptoms

through this therapy and then

538

:

you called the placebo effect.

539

:

Guys, I, I have a master's in

business and I know this like

540

:

People who are neuroscientists

about this shit.

541

:

Mike: Sure.

542

:

Sam: Sorry.

543

:

You're really passionate

544

:

Mike: about that.

545

:

No.

546

:

Yeah, I, look, I think it's good that

we've actually touched on this because

547

:

I think honestly particularly where I'm

at in functioning in the Canadian health

548

:

system, which sounds like has similar

issues to what you encountered with

549

:

previous iterations of VA and whatnot.

550

:

It's, I think the importance is

that people have options, right?

551

:

And so if they find that they've been

stuck in the sort of bureaucratic

552

:

mess associated with more sort of

top heavy healthcare bureaucracies

553

:

and not getting anywhere, I think

it's super important that folks like

554

:

yourself are offering people innovative

options that are also evidence-based.

555

:

But as you say honestly,

a lot of the psychiatric.

556

:

Is, they talk about the pharmacoeconomic.

557

:

Industrial complex, whatever they call

it, and how there's capture of the.

558

:

Schools, training programs,

the journals, the research

559

:

funding, and so yeah, absolutely.

560

:

To have an option like what

you're offering there at mind.

561

:

Sp is, it's, really encouraging I think

because as you say, you're getting

562

:

the results and you're looking to

expand and people are getting better,

563

:

which is the most important things.

564

:

So yeah, I think it's just fantastic to

offer people these options and help them

565

:

to get better as quickly as possible.

566

:

Sam: Yeah, Michael how

have you experienced that?

567

:

'cause, like how have you experienced

dealing with the Canadian health system?

568

:

'cause here it is just so owned

by the pharmaceutical industry.

569

:

It's wild.

570

:

Mike: Yeah.

571

:

Oh yeah.

572

:

No, we have that, it's hard on the

one hand, there are some people

573

:

that benefit from medications,

there's no doubt about it.

574

:

But on the other hand, it's hard for

people to explore different options

575

:

if they've had disappointing results

with medications and or psychotherapy.

576

:

I think it's increasingly, there are

some more options available, like RTMS,

577

:

but then that's still in many provinces

not covered by the provincial Oh really?

578

:

Health insurance system.

579

:

Again it's sad because it's often the

people who need the help the most, that

580

:

can't afford it, or they can't advocate

for themselves enough to know where to

581

:

look for other options and, so definitely

it's frustrating, but increasingly

582

:

like with different neuro clinical

neurostimulation programs and people

583

:

who, I think even just media like this,

people who can just watch and listen

584

:

to shows like this for free and just

increase their education and awareness

585

:

about different treatment options.

586

:

I think that's a big part of it because.

587

:

Up until recently, people have been

limited by gonna see their doctor

588

:

and not knowing where else to go

for help or for different options.

589

:

If they need a second or a third

opinion, they're not getting better.

590

:

And just trusting the system as it exists.

591

:

Which often doesn't serve

people very well in the end.

592

:

Sam: Yeah, that's a good point.

593

:

It also brings up another one.

594

:

I'm sure you've seen this as well, just

on TMS and on our TMS specifically, the

595

:

fact that we have to administer this

treatment over six weeks is criminal.

596

:

A normal course of TMS, as I'm sure your

audience knows, is about 36 treatments.

597

:

We get it done in about seven weeks.

598

:

The only reason that it takes

that long is because the insurance

599

:

companies won't let me bill for

more than one treatment at a day.

600

:

The studies out of the studies outta

Stanford with the Saint Protocol

601

:

and Magnus Medical are incredible.

602

:

They're doing a whole course of

TMS up to 50 treatments in a week.

603

:

Their data is showing that

90% of people respond to that.

604

:

That's insane.

605

:

Why there's such a, it's, there's a

zeitgeist in medicine that I don't

606

:

think people understand and it's

something that I keep having to bring

607

:

up, but you know the hippo there.

608

:

There's two really primary

things in medicine that doctors

609

:

are supposed to abide by.

610

:

First one, Hippocratic Oath

do no harm, and the second is

611

:

least invasive to most invasive.

612

:

You want to do the thing that is

gonna create the least amount of

613

:

potential biological harm or impact

before moving on to the next.

614

:

How in the hell are we saying.

615

:

For as a industry that a selective

serotonin reuptake inhibitor that

616

:

is changing your neurochemistry and

takes 10 weeks to work and then takes

617

:

a much longer tail to wean off of,

or you will have withdrawal symptoms

618

:

that make you wanna kill yourself.

619

:

How is that less invasive than using

a magnet to stimulate your neuron?

620

:

In an outpatient procedure that you can

walk away from that has very limited side

621

:

effects and incredibly low risk profile.

622

:

How is that, how does

that even make sense?

623

:

Mike: Yeah, no, you're right.

624

:

A hundred percent.

625

:

Again, it's there's a variety of different

factors, but what I find refreshing is

626

:

that I've chatted with, friend of mine in,

in Texas, who's an entrepreneur as well.

627

:

And part of what I, when I vent to him.

628

:

And I, when we talk sometimes,

and I say honestly, that the it's

629

:

not just a Canadian thing, but I

think for clinicians in general,

630

:

and there's good reason for it.

631

:

Ob obviously safety is very important,

but I think what's not encouraged so

632

:

much is the innovation piece, right?

633

:

And so for someone who's

more business minded, it's

634

:

understandable that there's a.

635

:

A frustration and as you're expressing

is almost like a, being mystified

636

:

about what's the problem, right?

637

:

We've got these treatments that

you showing incredible results

638

:

and the science is there.

639

:

The evidence is there.

640

:

So why is it not accessible

to everybody right now?

641

:

So having.

642

:

The frustration around the

regulatory limitations and this

643

:

sort of overly cautious approach

is certainly frustrating.

644

:

But again, kudos to you all and your

team for yeah, really just pushing the

645

:

frontier and making these effective

treatments available for people.

646

:

And also individualizing it as I

was saying before, like looking

647

:

at how can we best combine the

treatments that target these.

648

:

Processes in a way that gets people

relief as quickly as possible.

649

:

Sam: Yeah.

650

:

Tha thanks for saying that Michael.

651

:

I appreciate it.

652

:

It's, I was kinda shorthanded get patients

better faster, keep 'em better longer.

653

:

And if that's not your goal,

you're in the wrong industry.

654

:

Yeah,

655

:

Mike: a hundred percent for sure.

656

:

No, I think that's, that's a good

point to wrap up on for sure.

657

:

Maybe before we do what would, you

mentioned, you've got visions to expand.

658

:

What's next for Mind Spot Denver,

just in the near term and the future?

659

:

Are you looking to, broaden, different

clinics within Colorado and or outside

660

:

of the state or what are you guys.

661

:

Sam: We're actually currently seeking

some some investment to expand down to

662

:

Colorado Springs so that, that's the

other city down in the front range.

663

:

Once we do that I would love to see

our programming get become integrated

664

:

with the VA and the DOD on the d

on the Department of Defense side.

665

:

Helping the DOD retain the war

fighter is such a huge issue.

666

:

Retention has never been lower.

667

:

Recruitment has never been lower.

668

:

It is so important that we retain

these men and women just like myself.

669

:

Like I was a $10 million guy when I left

the Army, it took $10 million in six

670

:

years to replace someone with my skillset.

671

:

We can't afford to be losing

these people in droves.

672

:

We just can't.

673

:

Our nation's national security

really depends on us having a

674

:

fighting force that's ready to go.

675

:

And furthermore, the DOD when someone

gets injured should not just be kicking

676

:

the can down the road to the va.

677

:

We have created kind of our own

welfare state within the veteran

678

:

community with people who are getting

very reasonably, hurt both mentally

679

:

and physically in the military.

680

:

And they're getting the can

kicked down the road to the VA and

681

:

just say, Hey, here's 50 grand a

year for the rest of your life.

682

:

Just suffer quietly, please.

683

:

There's so many ways that we

can make this system better and.

684

:

That's my goal with all of this is

to expand the reach of these programs

685

:

and not just to veterans and active

duty, but to first responders as well.

686

:

The two primary reasons for

disability within the first

687

:

responder community are orthopedic

injuries, followed directly by PTSD.

688

:

We can treat these things.

689

:

We have the technology, we talked

about we talked about hyperbaric oxygen

690

:

therapy and that increase in stem cells.

691

:

The cool thing is we can take

those stem cells outta your blood.

692

:

Concentrate 'em just like you

would PRP in the hospital.

693

:

And we can take this super

PRP and stick it wherever we

694

:

want and it's your own cells.

695

:

There, there's so much left to do.

696

:

We're just the beginning of this and

my goal is for this to be national and

697

:

not just for, my business, but my goal

is to change the way that mental and

698

:

physical health are treated in this

country because we can do so much better.

699

:

Mike: Yeah.

700

:

Yeah, for sure.

701

:

Amen to that.

702

:

A hundred percent.

703

:

No, I think it's fantastic.

704

:

It's really inspiring.

705

:

I really appreciate your

passion and your vision.

706

:

And I would really encourage

viewers and listeners to check

707

:

out the links in the show notes.

708

:

I'll put links to Sam's Clinic and

all of his projects in the show notes.

709

:

I really appreciate your time, Sam,

and I encourage folks to check out.

710

:

Information, the content that

I'll put in the show notes.

711

:

So Sam, thanks again.

712

:

Really appreciate it.

713

:

Your courage both in terms of your

service and in the way you've.

714

:

Chosen to turn, the challenges and

the pain into healing for others

715

:

in this really inspiring way.

716

:

Yeah, these particularly, again, the

rapid acting nature of these interventions

717

:

that I really think are, looking to

transform the mental health landscape for.

718

:

Again, as you say, not only those who

serve or have been injured in service

719

:

first responders and the general public,

who are looking for alternative, but still

720

:

effective personalized treatment options.

721

:

Yeah, and also for viewers and listeners,

if you're listening and you're struggling

722

:

with these kinds of things, certainly

don't hesitate to check out the options

723

:

that are available at Mind Spa d or if

you know someone, please refer them.

724

:

Or share this episode.

725

:

Just help to inform

people and educate people.

726

:

So again, thank Sam, thank you so much

for your time and yeah, I just wish

727

:

you all the best with your work and

all your projects and your vision.

728

:

Sam: Thanks Michael.

729

:

I appreciate it.

730

:

It was it was great to come on the podcast

and have this conversation with you.

731

:

Mike: Okay.

732

:

All the best.

733

:

Take care.

Show artwork for The Neurostimulation Podcast

About the Podcast

The Neurostimulation Podcast
Exploring the frontier of interventional mental health.
Welcome to The Neurostimulation Podcast — a deep dive into the expanding frontier of interventional mental health.

Hosted by Dr. Michael Passmore, a psychiatrist specializing in neurostimulation and geriatric mental health, this show explores how cutting-edge interventions — from non-invasive brain stimulation (TMS, tDCS, and beyond) to ketamine-assisted psychotherapy — are reshaping the landscape of modern psychiatry and neuroscience.

Each episode bridges science, clinical experience, and human insight, featuring thought leaders and innovators who are redefining how we understand and treat the mind.

Whether you’re a clinician, researcher, student, or simply fascinated by the brain, you’ll discover practical knowledge, fresh ideas, and inspiring conversations that illuminate the evolving art and science of mental health care.

Subscribe for episodes that stimulate your mind, deepen your understanding, and connect you to the future of brain-based healing.

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About your host

Profile picture for Michael Passmore

Michael Passmore

Dr. Michael Passmore is a psychiatrist based in Vancouver, BC, with expertise in non-invasive neurostimulation therapies, geriatric mental health and ketamine-assisted psychotherapy. Having completed specialized training in multiple neurostimulation modalities, including electroconvulsive therapy at Duke University and transcranial magnetic stimulation at Harvard University, Dr. Passmore brings a robust clinical and academic background to his practice. Formerly the head of the neurostimulation program in the department of Psychiatry at Providence Health Care, Dr. Passmore now serves as a clinical associate professor at the University of British Columbia’s Department of Psychiatry. At Sea to Sky NeuroClinic (seatoskyneuro.clinic), Dr. Passmore offers interventional mental health treatments tailored to clients across Canada.​